Tag: Clinical Trials

  • Theoretical MDMA Synthesis in 3 Steps (Organic Chemistry)

    Theoretical MDMA Synthesis in 3 Steps (Organic Chemistry)

    In this post, we will look at MDMA’s history and its chemical syntheses. We will dispel myths about MDMA’s discovery and review the first kilo-gram scale MDMA synthesis published in a journal. We also dissect impressive recent clinical data that suggest ecstasy might help up to millions of people affected by PTSD. This might not…

  • Synthesis of Psilocybin and How Magic Mushrooms Rewire Brain Networks

    Synthesis of Psilocybin and How Magic Mushrooms Rewire Brain Networks

    Did you know that the active chemical in magic mushrooms psilocybin can rewire and make the human brain more flexible, translating into major therapeutic benefit in depression and other conditions? This has led to Australia approving specific medicinal use of psychedelics as the first country. You will be surprised to hear that psilocybin can be…

  • Are New Drugs Really Better Than Existing Ones?

    Are New Drugs Really Better Than Existing Ones?

    You probably know that drugs can get very expensive. What do you think – what percentage of new drugs actually provide significant therapeutic benefit compared to existing treatments? And do you think that drugs with a low clinical benefit are indeed priced any cheaper than highly beneficial ones? Beyond drug prices, we will also talk…

  • World’s Most Expensive Drug: Greedy or Fair?

    World’s Most Expensive Drug: Greedy or Fair?

    What is the most expensive drug in the world? Imagine a single dose of medicine priced at $3.5 MILLION. Since the approval of the gene therapy Hemgenix in late 2022, this is a reality. This eye-popping price is easy to scrutinize, especially if you know the truth behind most newly approved drugs. Drug manufacturers think…

  • Synthesis and Chemistry of Ibogaine

    Synthesis and Chemistry of Ibogaine

    The psychedelic ibogaine has built a reputation as an anti-addiction magic bullet. By now even have the Wolf of Wallstreet vouching for it. Drug manufacturers who fuelled the opioid crisis are forced to blow billions on lawsuit settlements. The state of Kentucky recently announced they might use double-digit millions for ibogaine research. Maybe you’ve heard…