Tag: Pharmacology

  • Thalidomide Tragedy: Horror Drug or Miracle?

    Thalidomide Tragedy: Horror Drug or Miracle?

    The thalidomide tragedy was the biggest “man-made disaster apart from war”. This molecule’s structure looks simple and innocent, but a chiral carbon gives rise to two enantiomers with different pharmacological effects. While one isomer was a safe sedative, the other one led to limb malformations in thousands of babies. We will check out how this…

  • Synthesis and Chemistry of Ibogaine

    Synthesis and Chemistry of Ibogaine

    The psychedelic ibogaine has built a reputation as an anti-addiction magic bullet. By now even have the Wolf of Wallstreet vouching for it. Drug manufacturers who fuelled the opioid crisis are forced to blow billions on lawsuit settlements. The state of Kentucky recently announced they might use double-digit millions for ibogaine research. Maybe you’ve heard…